The ECOTOXicology Knowledgebase (ECOTOX) is a publicly available web-based database providing curated single-chemical toxicity data for aquatic life, terrestrial plants, and wildlife. For over 30 years, ECOTOX has curated ecologically-relevant toxicity data to meet the systematic review and data transparency needs of the U.S. EPA for risk assessments and regulatory decisions. Relevant toxicity data are identified and curated through systematic and transparent procedures to conduct comprehensive literature searches, screen references, apply acceptance criteria, and extract all pertinent study and effects information. Currently, ECOTOX includes data for more than 12,000 chemicals from over 51,000 references. These data can be accessed via an interactive user interface and downloaded for ecological risk assessments, development of Adverse Outcome Pathways (AOPs), species extrapolation, and serve as a data source for the development of chemical screening and assessment tools for various regulatory applications.
This webinar will provide an overview of ECOTOX including a summary of the literature search, review, and data curation procedures, and detailed examples of querying/downloading data using the interactive ‘Explore’ module to investigate and visualize the data available, the ‘Search’ module to directly query specific species, chemicals, or effects, and the ‘Help’ page to access documentation on processes, controlled vocabularies, and definitions. For more information visit the U.S. EPA’s ECOTOX website: https://www.epa.gov/ecotox/